MOTS-c 40mg Vial (Mitochondrial-Derived Peptide)

Welcome to the official VitalisLabs UK product page for MOTS-c 40mg. Encoded within the 12S rRNA region of the mitochondrial genome, MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide that plays a central role in mitochondrial-nuclear communication, metabolic regulation, and cellular stress responses.

Buy MOTS-c 40mg UK — High-Purity Research Grade

When investigating mitochondrial gene regulation, metabolic signaling, and adaptive stress pathways, purity and sequence fidelity are essential. When you buy MOTS-c 40mg UK directly from VitalisLabs, each 40mg vial undergoes rigorous third-party testing via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to confirm exact sequence identity and batch consistency.

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|                    PRODUCT SPECIFICATION OVERVIEW                     |
|                                                                       |
|  * Product Identifier: VL-MOTSC-40                                    |
|  * Unit Content: 40mg per vial                                        |
|  * Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-  |
|             Leu-Arg (16 Amino Acids)                                  |
|  * Purity Level: >99.0% (HPLC & MS Verified)                          |
|  * Physical Form: Freeze-Dried / Lyophilized White Powder             |
|  * CAS Number: 1627580-64-6                                           |
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|  [ Download Batch COA Certificate ] ---> Opens PDF                    |
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Primary Research Pathways for MOTS-c

The MOTS-c peptide UK researchers analyze is cited across diverse areas of cellular biology and metabolic physiology:

1. AMPK Pathway Activation: Promotes the phosphorylation of 5′ AMP-activated protein kinase (AMPK), acting as a cellular energy sensor to regulate glucose uptake and fatty acid oxidation.

2. Folate-Purine Synthesis Modulation: Interacts with the folate cycle and inhibits the de novo purine synthesis pathway, leading to AICAR accumulation and subsequent AMPK activation.

3. Mitochondrial-Nuclear Translocation: Translocates to the cell nucleus during metabolic stress, binding to ARE-containing promoters (Antioxidant Response Elements) alongside Nrf2 to regulate adaptive gene expression.

4. Exercise-Mimetic & Metabolic Homeostasis: Serves as a major model compound for studying systemic insulin sensitivity, muscle glucose metabolism, and physical endurance adaptation.

Technical Specifications: MOTS-c 40mg

Reconstitution & Handling Protocols

1. Storage Prior to Use: Keep unopened lyophilized vials frozen at -20°C in a dry environment.

2. Reconstitution Solvent: Reconstitute using sterile laboratory-grade water or phosphate-buffered saline (PBS).

3. Dissolution Method: Direct the solvent stream gently down the glass inner wall. Allow the lyophilized cake to dissolve completely without vigorous shaking to preserve secondary structural integrity.

4. Post-Reconstitution Handling: Store reconstituted solutions refrigerated at 2°C to 8°C for short-term active assays or freeze in aliquots at -80°C for long-term storage.

Compliance Disclaimer: All buy research peptides MOTS-c UK products provided by VitalisLabs are strictly intended for laboratory in vitro testing, chemical evaluation, and scientific research. They are not intended for human consumption, clinical usage, or therapeutic administration.