NAD+ 1000mg (Nicotinamide Adenine Dinucleotide)
Welcome to the official VitalisLabs UK product page for NAD+ 1000mg. Essential to every living cell, Nicotinamide Adenine Dinucleotide ($\text{NAD}^+$) is a critical coenzyme found in mitochondria and cytoplasm, serving as a primary electron transporter in cellular respiration, oxidative phosphorylation, and enzymatic signaling pathways.
Buy NAD+ 1000mg UK — High-Purity Analytical Coenzyme
In cellular energetics, DNA repair, and sirtuin activation assays, chemical purity and molecular stability are paramount. When you buy NAD+ 1000mg UK directly from VitalisLabs, each high-dose vial undergoes strict third-party verification via High-Performance Liquid Chromatography (HPLC) to ensure consistent analytical grade purity and batch-to-batch reliability.
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| PRODUCT SPECIFICATION OVERVIEW |
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| * Product Identifier: VL-NAD-1000 |
| * Unit Content: 1000mg (1g) per vial |
| * Purity Grade: >99.0% (HPLC & UV Spectrophotometry Verified) |
| * Physical Form: Freeze-Dried / Lyophilized White Powder |
| * CAS Number: 53-84-9 |
| * Chemical Formula: C21H27N7O14P2 |
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| [ Download Batch COA Certificate ] ---> Opens PDF |
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Primary Research Pathways for NAD+
The NAD+ coenzyme UK researchers analyze is central to a broad spectrum of cellular mechanisms:
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Mitochondrial ATP Production: Serves as the principal electron acceptor ($\text{NAD}^+ \rightarrow \text{NADH}$) in glycolysis, the Krebs cycle, and electron transport chain complexes.
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Sirtuin Activation (SIRT1–SIRT7): Acts as an indispensable rate-limiting substrate for $\text{NAD}^+$-dependent deacetylases involved in gene expression, chromatin remodeling, and metabolic regulation.
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PARP-Driven DNA Repair: Serves as a required cofactor for Poly(ADP-ribose) Polymerase enzymes involved in single-strand DNA break detection and structural genomic maintenance.
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CD38 & Cyclic ADP-Ribose Signaling: Functions as a precursor in calcium signaling pathways that regulate immune cell function and cellular homeostasis.
Comparative Analysis: NAD+ vs. NMN Precursors
In metabolic and longevity research, understanding direct coenzyme administration versus precursor conversion is key to experimental design:
| Parameter | Direct NAD+ 1000mg | NMN (Nicotinamide Mononucleotide) |
| Molecular Structure | Complete Dinucleotide ($\text{C}_{21}\text{H}_{27}\text{N}_{7}\text{O}_{14}\text{P}_{2}$) | Mononucleotide Precursor ($\text{C}_{11}\text{H}_{15}\text{N}_{2}\text{O}_{8}\text{P}$) |
| Direct Enzyme Binding | Binds directly to SIRTs, PARPs, and CD38 | Requires enzymatic conversion via NMNAT enzymes |
| Primary In Vitro Focus | Direct intracellular coenzyme depletion & saturation models | Transport dynamics & biosynthesis rate-limiting assays |
Technical Specifications: NAD+ 1000mg
| Parameter | Specification Detail |
| Chemical Name | $\beta$-Nicotinamide Adenine Dinucleotide ($\text{NAD}^+$ free acid) |
| CAS Number | 53-84-9 |
| Molecular Weight | ~663.43 g/mol |
| Solubility | Freely soluble in sterile water and aqueous buffer solutions |
| Storage Parameters | Store desiccated at -20°C in the dark; highly hygroscopic |
Reconstitution & Laboratory Handling Protocols
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Storage Prior to Preparation: Store unopened, freeze-dried vials at -20°C in a dry environment protected from light exposure.
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Hygroscopic Precaution: Allow the vial to equalize to room temperature before opening to prevent moisture condensation on the lyophilized cake.
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Reconstitution Solvent: Reconstitute using sterile laboratory-grade water or phosphate-buffered saline (PBS).
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Post-Reconstitution Storage: $\text{NAD}^+$ solutions in aqueous media degrade naturally over time; store prepared solutions at 2°C to 8°C for short-term assays or aliquot and freeze at -80°C for extended stability.
Compliance Disclaimer: All buy research compounds NAD+ UK products supplied by VitalisLabs are strictly intended for laboratory in vitro evaluation, chemical testing, and scientific research. They are not intended for human consumption, IV infusions, therapeutic applications, or clinical usage.







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